The magnitude of that elusive placebo effect might be a bit lower in future studies…
I saw a reference to interest in performing tests on subjects to screen out folks who have the met met polymorphism of the gene that codes COMT…
Genetic biomarkers of placebo response: what could it mean for future trial design?
Subjects with COMT met/met polymorphism have predisposition for significantly higher placebo response. Approximately 25% of the population is of the met/met type. Subjects can be easily tested for this polymorphism.
