That’s a complex issue that lead me to some genuine questions :
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Can you just blame the actor ? Is the performance an issue or the writing/directing ? If Leto did a bad job isn’t it because the writer and the director did a bad job at directing him in the good path ? Is it a case of bad acting or poorly written character ?
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Can you forbid actors to be cast in some role ? how do that work ? Where do you put the limit ?
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Cinema is art and not all director have a “naturalistic” approach. Some characters are not realistic and can be “wrong” on purpose. Is it bad ? I guess my point here is cinema ≠ reality.
I agree the lack of representation and even more the bad representation is harmful. Cinema (has much as over media) have a huge responsibility, and a good start may be to include trans people in the writing even more than in the acting.