The Flat Earth hypothesis fails to meet the criteria of a useful scientific hypothesis whenever it includes unfalsifiable claims.
Yes, as an idea it can be scientifically evaluated (and easily falsified on those claims it makes that are falsifiable). But you can also scientifically test for angels, as long as you haven’t defined them in such a way that no test will ever be adequate.
The premise of Simulation Hypothesis is a moving target where no data could prove or disprove it.
It’s a thought experiment, and a fun exercise, but its premise rests on similar foundations as theorising what an angel’s wingspan would be, based on what we know of birds.