You have plain old normally aspirated V6, V8, diesel V8 (?,) Turbo V6, Turbo Hybrid V6 and Super Charged V8 FACTORY models of the F150, I think. People who buy the Raptor and whatever the other Tremor or Ford performance packages are, are typically bought by folks who want to hoon around. Generally the hooning is done offroad.
I would figure on 1-2 short 30-45 minute coffee stops somewhere along the route, depending on how much electricity you intend to use at the campsites with the truck. If you are booking sites with electricity then you are golden, to an extent. IIRC my experiences with hookups at California state sites were 15amp circuits.
My most frequent road trip is the 400miles of Los Angeles to San Francisco. 300-mile range of the F150 suggests 1 stop for 45 minutes or so mid-way. I frequently will not stop. That prolonged driving time without stopping is very bad for my back. I doubt most of America has my lower back but I think a 45 minute stop every 3-4 hours of driving is probably pretty realistic. I understand the onboard system will guide you to drive to near 20% battery capacity and have you to charge up to around 80%, rinse and repeat.
I love the idea of this truck for that drive and the other daily uses I get out of mine now, just without gas.