Just don’t put negative matter in the thing.
Best case the electric field of the molecules push against each other like normal matter, leaving the slightly unequal force of the repulsion against Earth’s gravitational field to force it to press one-gee harder on the top plate, but the equal and not-opposite pressures on the two plates mostly cancel out and the negative matter is crushed like normal matter.
But worst case the negative matter mutually erases itself and an equal mass of the press plate’s molecules on contact, suddenly changing the masses of countless subatomic particles and releasing a hail of deconfined quarks that would destroy the Earth!
Just say yes to negative matter…so it goes away.
Oh gawd I’m glad it’s Friday!