About the hypothetical BRCA scenario people keep raising –
I know someone who tested positive for the variant through 23andme, and made an appointment at a specialist medical center where she wound up seeing the head of oncology, as part of its high-risk program. She asked if she should repeat the test for confirmation. He consulted with the center’s board of advisors, and their collective judgement was no. (She also has family history of BRCA cancer, and came back as having the same specific variant as her mother.)
So it’s interesting that the practicing medical authorities are either confident in the test, or their assessment is equally at fault.
