I know a Marriott that let us bring our 80 lb. pitbull mix; of course, we listed her as a 50-lb boxer mix.
She also had a sweet-looking face and an even sweeter disposition. She also was welcomed at their Residence Inn in Las Vegas, San Diego, Palm Springs (most of the chain, if not all, are pet-friendly), and their Courtyard in SLO.
ETA: I know there is size discrimination and I don’t get it. Also, I’m not sure if one can downsize a Great Pyrenees. They are pretty damn big.