The difficult part is that skepticism itself can become a person’s guiding principle, to the point of deliberately disagreeing with any mainstream belief, or real truth.
Any “truther,” whether 9/11, Flat Earth, QAnon, etc, starts out as a skeptic, someone who believes that we are being bamboozled, that the truth is different from what they want you to believe.
So along with skepticism, you need a strong understand of both science and history – how truth is discovered and tested.