I was diagnosed with AS in my 30s following a bout of Uveitis (fortunately the eye specialist knew about AS connection) until then I had suffered from pain in my neck, lower back and most major joints – and, virtually unnoticed, some upper vertebrae were fusing together. After various drug treatments we settled with self-administered adalimumab injections every fortnight, combined with regular exercise, this has been successful in reducing further advances in fusing and made the pain into a background thing.
I find if I can exercise or even just walk through the pain it will become insignificant for a while. Sitting still is a problem.
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