Not sure about the recent DRMs, but I’ve had good luck in the past with stripping DRM from my Amazon-purchased stuff using instructions from the standard sites. It’s a constant arms race, though, and you have to time it just right so you’re at a point where the latest DRM has been cracked, but Amazon hasn’t yet swept in to take the ability away again.
I hear good things about Kobo e-readers - once my Voyage finally gives up the ghost, that’s probably where I’ll go.