Multi-panel, but I always wondered about Andy Capp. I think my grandfather might have read it (he, and his newspaper, both still referred to Snuffy Smith as “Barney Google” years after the name change). But I never knew anyone to read Mary Worth or Judge Parker.
Just found out that Funky Winkerbean still runs, somehwere, but that Boner’s Ark does not. (ha ha, “boner”)