NASA had Apollo-era plans to send humans to Mars and Venus

In terms of ‘actual successor hardware existing’ Apollo era hardware isn’t antiquated, since we largely didn’t bother to ever build any successor hardware; but at a component and manufacturing level, there have been some significant changes.

Take this story as an example: the concept could hardly be more ‘everything Apollo is new again’; but the sheer number of changes in design, fabrication technique, and other details, even when handed the goal of ‘Yeah, dust off a vintage F-1 engine and build a new one.’ is pretty significant.