I have used NoScript and AdBlock for many years, but just last week I started using Self Destructing Cookies. Like NoScript, there’s a initial acclimatization effort, but so far I really really like it.
I have no affiliation with any of the people who make these tools, although I have paypal’d a few zuleks to the NoScript guy. I cannot recommend them to anyone who is only minimally computer literate, they are too powerful for novices.