Not quite? Factors like epigenetics make it clear that there is much more to the development of an organism than the expression of single genes, with all sorts of combinations and environmental effects allowing a tremendous variety. But if you consider several generations, it still seems like the genome provides a stable core.
Because really, what things like epigenetics are about are the different phenotypes that a genome can be expressed in. Depending on circumstance the same DNA will give a muscle cell or neuron, in a worker or queen bee, or so on; they give surprisingly huge ranges. But those ranges still have limits, and from all I have seen, the way they are extended is still basically changing of the genome through random mutations and shufflings, selected by what that enables.
There is an amazing world of details here, much of it still to be discovered, but it really seems to be less that natural selection is incomplete, and more that there is much more to it than often given credit.
