Hmm. I wonder if the RPi4 is capable of powering a 2.5" HD from the USB3 port? I’ve always used a powered hub for that (dropping new Pis into the old setup), but I didn’t realize that the RPi3 had improved output until I tried to get a high-gain Wi-Fi adapter to work with a RPi2. I should test that with my RPi3B+.
It’d be nice not to have to buy a USB3 powered hub, and simplify “everything in one box” projects.