I think if you compare the two directly, then you can tell the difference. If you have never smelled both of them, which ever you smell first will most closely resemble the other. That is if you never smelled weed but have smelled a skunk, the skunk smell is the closest analogy you can come up with to compare it to.
This reminds me, I used to have this sweatshirt which I swear to god smelled sorta skunk like if I wore it and sweat in it. I washed it several times and I could still smell it. It was faint, but it was enough that I decided to retire it to the closet at some point. No idea way. Probably had some synthetic fiber my body didn’t like.
