Count Orlok is the vampire in Nosferatu - indeed a “mysterious fellow… who seems to be part monster”.
The pseudonymous Jukes and Kallikak families were touted by American eugenicists as concrete examples of why poor and disadvantaged rural populations should be forcibly sterilized (and indeed, many were). Wikipedia has articles on both; eugenics history is a huge and complex subject, with many interesting parallels to modern Internet Sciencism.