@KingGhidorah We were the institute that made the strong case for transmissible Alzheimer and CAA (Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy | Nature). I want to point out that it is fairly easy to identify the replicating species in prion mechanisms. In Alzheimer it can be tau protein and amyloid-beta. In CJD, mad cow, CWD etc. it is the prion protein PrP. Same mechanism, but different protein. So, no - Alzheimer is definitely not caused by undetected mad cow transmissions.
@ejeffrey Alzheimer, Parkinson, Creutzfeldt-Jakob each have their own protein. Very similar replication mechanism, but so far only “proper” prions, i.e. made up from prion protein PrP have been shown to be infectious in animals and humans under real life conditions. Noone quite knows why.
