I wouldn’t bet against a clever solvent extraction prior to drying; but even if that problem were solvable the excercise wouldn’t be any less perverse. Tobacco is sort of an oddball in that the drug part(while crazy addictive) is markedly less dangerous than the delivery mechanism. People drinking non-alcoholic beer or mocktails are skipping the relatively dangerous ingredient. Somebody using de-nicotinized tobacco is getting most of the cancer without the perks.
You might as well go hunting for drug-free dirty needles.
