It’s much more important to get rid of the products of combustion, which are the really nasty carcinogens and probably the source of the second, possibly more massively addictive chemical, the MAOI.
The current best research says nicotine isolate is not terribly addictive; when people who have never smoked wear patches or chew the gum or drink hangover cures, withdrawal is light or even unnoticed. It appears the bigger issue is the combination of the MAOI and nicotine, with the MAOI being the greater contributor, since people who take MAOIs for other conditions have issues withdrawing from those, too. (This study is small, but is consistent with observed behavior on controlled populations of smokers - usually people with schizophrenia living in group homes; there’s a massive link between schizophrenia and smoking as a form of self-medication. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC19495/)
