Curious robotic syringe-in-a-pill completes successful human trial


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That gas inflates the balloon, and the pressure of the inflating balloon pushes a dissolvable microneedle filled with a drug of choice into the wall of the intestines.
Human intestines lack sharp pain receptors, so the micro-shot is painless.

Really? so much for “Searing gas pain land”


two chemicals trapped on either side of the pinch point to mix and produce carbon dioxide.

Don’t they know that’s a greenhouse gas? Why do they hate polar bears?


Brainstorming for these types of swallowed solutions has to be fun!

“Ok, what else could we fit in the capsule?”


“OK, what other food can we hide the capsule in?”

I recall hearing about research on an inflatable balloon at the end of a catheter for angioplasty or stent installation, that, when inflated, poked a tiny needle into the artery to inject a drug that would help keep the artery open.


What is the use case for this device :interrobang:




Drugs that can’t make it through the stomach due to the highly acidic conditions, but need to be delivered to the GI tract. It’s a way to take it (efficiently) orally instead of (inefficiently) through IV.




I can vouch that this is, at least mostly, a current practice. Family friend had the catheter enclosing the camera and balloons inserted into his arm directly to his heart. I think the baloons were inflated to bust the plaque blocking certain arteries? Or to widen the artery for the stint maybe.


You guys are reminding of a time when I completely and loudly cursed out a nurse while she was removing my catheter post op a few years ago. I think I scared her. I apologized after and we were cool but, damn, damn that was unpleasant.


Common practice for really narrow stenoses (narrowings of the artery) is to go in with a balloon, open it up, then go in with the stent to hold it open.

There are also some crazy balloons out there. There’s one called a cutting balloon that has tiny razor blades on it, that is used for tough, calcified lesions that regular angioplasty balloons can’t get open.


Was that a catheter in a blood vessel or a catheter . . . somewhere else?

Somewhere else catheters are definitely unpleasant.


Double espresso please.

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