Not really. Evolving a resistance to a particular antibiotic or other drug is (relatively) easy, because they usually target a fairly specific part of the microbe metabolism. Evolving a resistance to something like high concentrations of ethanol is hard, because you need to radically redesign huge parts of the microbe’s make-up.
For example, the reason alcohol-based hand sanitizer kills coronavirus is because the alcohol works as a solvent on the lipids making up the envelope surrounding and protecting the core of the virus. And since the lipids are scavenged from the parent cell’s membrane, the virus is not going to evolve a defense easily.