Depends on what is in the substance. The substitute of some substance may be worse, or may be better, than the original. See for example tofu (“to-phooey”).
In case of comfort foods, however, the taste and associated variables take precedence.
If you eat healthy, you won’t live longer. But it’ll feel that way.
You asked, and also answered yourself in that very post?
Processed cheese is significantly cheaper than proper cheese here in Canada, I don’t know about the US. Though I presume the “cheese substitute” being used in the case of this story isn’t processed cheese, that would be… Gross.
Fun aside: it was quite a shock to my Irish wife to learn just how expensive cheese is here (Canada) compared to Ireland.