Plague has been endemic here, since basically forever. There are isolated cases in the Southwest almost every year. We mostly have good enough sanitation to keep it from spreading. I dread the day when it breaks out in some place like an ICE detention camp. I’m sure there’s a certain political faction in the USA that salivates at the idea, though.
Uhm, it’s not at the head of my list of worries, either, but multidrug-resistant Yersinia pestis is a thing.