Alas, after a quick skim, I saw nothing about direct topical application at the time of expulsion. If that becomes part of the therapy, they might be able to find some people to assist with sourcing.
Would it help if they were on fire? Science says try it out!
That’s because they’ve finally asked a scientist to write about a scientific issue. It makes for a stark contrast to their usual stable of shitty opinion writers.
The rest of the “return to school” coverage is short on science, long on “we’re tired and worried and think of the children” fluff. Ms. Teitel, however, nails it.
@LutherBlisset That Guardian piece, along with @Jesse13927 the piece from CNN, and @catsidhe the (economy ≡ healthy people) piece seems to be part of a growing “oh f**k, it’s not just dead or alive” realization.
Add to this Armine Yalnizian’s analysis (who along with Robert Reich, Christine LaGarde and Raguram Rajan, is one of the few economists I listen to) I can only hope there’s a thought gaining traction about the long-term effects of this.
But this has only been possible because we managed to get so many boosters out. We’re at 58% of the population boosted now (with better coverage in vulnerable and older groups), one of the highest in the world behind Chile and Iceland.
Meanwhile, this horrible spike in cases looks like it’s coming for the rest of the world.
OMG, That “direct from catheter, drink from the spigot” bit… eeeeee.
I almost posted a popcorn gif as I settled in to read it, but then I bet they would put pee on their popcorn, too.
There is so much dangerous info there.
One of my best college friends has gotten on this general train, it’s so sad. Gone all anti-vaxx, does DIY enemas, it’s wild to think we both got a college-level liberal arts education but somehow she surrendered her critical thinking skills in the time since.
Figured I would put this here as a brief reference to the various treatment options for covid, and comments on limitations thereof. Might become valuable information as we seem to have given up on preventing infections. Evushield was a new one on me. Pre-exposure prophylaxis for something that is pretty much omnipresent is, just wow…
Dear Colleagues,
At UVA Health, we are committed to offering our patients the best COVID-19 treatments available. To support you in understanding the newest options, we have prepared the overview below. It provides a link to a new treatment decision-making tool that you are encouraged to use as well as details of newly-approved monoclonal antibody and oral antiviral treatments for COVID-19.
Monoclonal Antibodies Update
Evusheld Monoclonal Antibodies for Pre-exposure Prophylaxis I The FDA has issued emergency use authorization for tixagevimab-cilgavimab (Evusheld) intramuscular injections for use in pre-exposure prophylaxis in adults and children ≥12 years older and ≥40 kg who have moderate to severe immune compromise and may not mount an adequate immune response to COVID-19 vaccination. Evusheld is not indicated as a treatment for COVID-19 or for post-exposure prophylaxis in those exposed to someone with COVID-19. Evusheld is not a substitute for vaccination. Supply is very limited, so patients will be prioritized by biomedical risk factors until supply catches up with demand. Referrals are now being accepted for patients within category 1. Learn more about this option and how to refer: UVA Pre-Exposure Prophylaxis for COVID-19 (Evusheld): FAQ. Providers can help patients search the COVID-19 Treatment Locator - Monoclonal Antibodies site to find locations where doses are available.
Outpatient monoclonal antibodies for COVID-19 treatment I Supplies of COVID-19 Monoclonal Antibodies (mAb) for treatment are also extremely limited. This shortage includes Sotrovimab, which is the only currently available monoclonal antibody for treatment of COVID-19 infection that may have activity against the dominant circulating Omicron variant. Referrals are being prioritized for the highest risk immunocompromised patients until supply catches up with demand. Providers can help patients search the COVID-19 Treatment Locator - Monoclonal Antibodies site to find locations where doses are available.
New Outpatient Oral Antivirals
The FDA has authorized the first oral antivirals for the treatment of mild to moderate COVID-19 infection in outpatients at high-risk of progression to severe disease. Available by prescription only, both treatments should be started as soon as possible after the diagnosis of COVID-19 using either PCR or antigen testing and within 5 days of symptom onset. Here is an overview of each medication:
Paxlovid | This drug is a combination of the anti-viral nirmatrelvir and the boosting agent ritonavir. It is authorized for treating patients ≥ 12 years of age and ≥ 40 kg. There are a number of drug interactions to be aware of and co-administration with certain drugs highly dependent on CYP3A for clearance may be contra-indicated. A full drug history should be obtained prior to prescribing, and clinicians with less experience prescribing ritonavir-boosted drugs can refer to this drug-drug interaction guide and consult a pharmacist. Renal adjustment of dosing may be required and treatment is not recommended in severe liver impairment.
Lagevrio (molnupiravir) | This antiviral is authorized for use in adults when no alternative COVID-19 specific treatment options that have been authorized or approved by the FDA are available due to lower expected efficacy. Molnupiravir should be avoided in pregnancy due to concerns related to mutagenesis and in children due to possible bone and cartilage toxicity.
Accessing Antiviral Supplies | The Virginia Department of Health authorizes the distribution of these agents to health-systems and pharmacies and monitors for adherence to the EUA for continued access to the therapy. UVA Pharmacy has requested, but not received, a supply of these medications from the VDH. Providers can locate other pharmacies in the Commonwealth that may have supplies of these oral antivirals here: COVID-19 Treatment Locator - Monoclonal Antibodies. Providers are responsible for using these drugs as specified under the terms of their authorization, as detailed in the package inserts.