What “butthurt” is meant to mean depends, of course, upon the intentions of the speaker. But I have definitely heard it used often in a rapey context. For example: “Sure, he got royally fucked, so now he’s butthurt.” and other similar uses which really are meant to convey, with whatever level of seriousness, a degree of sexual violence, a scenario of being anally dominated. So I think it tends to be distasteful in use, but everything depends upon context. IF you prefer to not perpetuate a paradigm of sex as power struggle, you might want to consider saying something else.
Some terms cause offense for what they mean literally - such as “fggt” - a thing that ones lights on fire. I had a friend who was murdered by being burned alive, and it is distressing for me to think about even now. OTOH consider “nggr” - which literally means “black” - but still caries an extremely strong pejorative flavor because of its usage.
I don’t agree with getting overly prescriptive about what to say, and what not to say, in terms of codifying blanket PC regulations for self-censorship. But it would be ignorant and awkward to choose to remain unaware of the ways people can and will interpret way you say. That’s just lazy.