that looks and sounds right. thanks.
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Quantitative particle count fit testing is a solved problem that is already implemented in the industry, itâs just not standard because the equipment to do it costs more.
To test an FFR, you have to punch a port into a sacrificial mask for the sampling tube - punches and grommets are used. Another sampling tube samples from just outside the mask. The difference between the two sampleâs particle counts is the total inward leak rate. The qualitative fit test does use up at least one FFR per user - which is one of the reasons why fit testing was often omitted during the N95 shortages.
For elastomeric respirators, manufacturers sell adapters for the sampling port.
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Canada may be somewhat outside of your jurisdiction, Governor.
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bejeebers! what a jackass.
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Hey, why you wanna insult my pet jackass like that?!
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We do have civil forfeiture in 
(it occasionally bubbles up to public awareness but isnât quite the law-enforcement fundraiser it is in the 
). I think GoFundMe is just getting ahead of what would otherwise be rather unfortunate (for it) government action.
Edit: With so many Canadians in Florida, maybe DeSantis thinks Florida has become a province⌠
âŚ
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okay, hows about
what a hackass!
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We? Who does he think he is, the Queen?
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Dug out the science. My (usual disclaimer here, Iâm not a medical person or physician) impression is that this story concurs with things to which @anon29537550 has alerted us. âAptamerâ doesnât seem to have come up in our discussions. I found a survey article and they sound like some seriously cool work. Berlin Curesâ BC 007 seems to have been âon the shelfâ and had success in an initial clinical trial with 4 Long COVID patients, leading to near total remission.
- Retinal Microcirculation as a Correlate of a Systemic Capillary Impairment After Severe Acute Respiratory Syndrome Coronavirus 2 Infection (Erlangen study looking into blood cells losing flexibility and not passing through small capillaries as a cause for Long COVID)
- Aptamer BC 007 - Efficient binder of spreading-crucial SARS-CoV-2 proteins (the work is a year and a bit underway)
- Aptamers Against COVID-19: An Untested Opportunity. (Thereâs definitely a commercial angle to this, but thatâs life)
- Study to Investigate the Safety, Tolerability, Pharmacokinetics and Mode of Action of BC 007 (nothing bad happened in initial trials of BC 007).
- Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms (Edit: missed this paper, links the auto-immune problems to COVID and points to the treatment in the next paper)
- Case Report: Neutralization of Autoantibodies Targeting G-Protein-Coupled Receptors Improves Capillary Impairment and Fatigue Symptoms After COVID-19 Infection (the formal report on an initial Long COVID trial)
Within 48 h after a single BC 007 treatment, GPCR-AAbs were functionally inactivated and remained inactive during the observation period of 4 weeks. This observation was accompanied by constant improvement of the fatigue symptoms of the patient, taste, and retinal capillary microcirculation.
- Physical phenotype of blood cells is altered in COVID-19 (very cool, but fundamentally straightforward measurement approach âreal-time deformability cytometryâ. Strictly âmechanicalâ measurements, but this pegs my very geeky ânice workâ meter. Dr. Bettina Hohbergerâs group are looking like rock starsâŚ)
We identified significant and persisting changes of cell size and mechanical properties in acute-phase and post-COVID-19. These changes might be predictive for cell functionality such as oxygen delivery.
Work continuesâŚ
Iâll tentatively and totally amateurishly get excited by this. Fingers crossed itâs a breakthrough.
Edit: missed a key paper. Edit again: so much cool stuff⌠Edit again: missed an important paper in the sequence
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I doubt anything comes of this but people did notice.
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Thank you for your work digging that up.
I will have a hard time not getting excited about this. But then, it would not be the first time, and usually this doesnât end well for meâŚ
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On a side note, 15 Reagan appointed judges still sit on the bench. Theyâve been there from 35 - 37 years. Six judges he appointed are still serving in senior status, they have served 40 years.
Can we please rethink term limits for appointed judges? Or maybe a retirement age? I have no urge to work past tomorrow let alone into my 80s unless I need to live indoors but these judges just need to get a hobby. That goes for both sides.
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term limits maybe. but thereâs nothing wrong with old people who - if they can do the job and want to - keep working. i hope to be old someday and would appreciate the choice
our bigger problem is all the people who canât stop working when they need to because we donât have a proper retirement system
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I assume the lawyer knows it would not be in his best interest to respond with: you are asking me to risk death in order to present the case in this courtroom?
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Have you noticed that kind of thinking more since the pandemic began?
Well, yes, in the way our leaders talk about the risks, the mortality, about people with severe illnesses, as if theyâre a write-off. I am so tired of having to assert myself. What kind of world is this where we have to defend our humanity? What is valued in our society? Clearly, someone who can walk and talk and has zero comorbidities. It is an ideology, just like white supremacy. All our systems are centered around it. And so many people are discovering that theyâre not believed by their doctors, and this is something that a lot of disabled and sick people have long experienced. We want to believe in this mythology that everybodyâs equal. My critique is not a personal attack against Dr. Walensky; itâs about these institutions that historically devalued and excluded people. Weâre just trying to say, âYour messaging is incredibly harmful; your decisions are incredibly harmful.â
Which decisions?
The overemphasis on vaccinations versus other mitigation methods. That is very harmful because people still donât realize, yeah, there are people with chronic illnesses who are immunocompromised and have other chronic conditions who cannot get vaccinated. And this back and forth, itâs not strong or consistent about mask mandates. With omicron, there is this huge pressure to reopen schools, to reopen businesses. Why donât we have free tests and free masks? Youâre not reaching the poorest and the most vulnerable who need these things and canât afford them.
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