Ongoing coronavirus happenings

caitlin-doughty-■■■■■

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On the other, hand, you’ll still die. So there’s that.

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But it doesn’t count, don’t you see? Only definitely, conclusively proven Covid-19 cases count, and only if they happen to perfectly healthy people. Actually, now that I think about it, if you have Covid, you are not perfectly healthy, so no one can die of Covid! Pandemic solved!
(I hope this is unnecessary, but /s for any who doubt.)

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Thumbs up to you from the grave by Jonathan Swift!

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Mmmmmm
baby back ribs.

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Tricky little inverse sections of RNA linked to a fluorescent tag that only becomes available when the section of RNA has a perfect match. The way most of these fluorescent tags work, there is a section of RNA that has a series of nucleic acid bases that are a mirror to the ones for the virus.

Let’s use a series of 8 bases as an example (though these sensors are usually much longer, up to 100-ish bases): ACGUACGU. That would correspond to the virus RNA section with the code UGCAUGCA. Then the sensor also has a fluorophore, often Fluorescein, bonded to the RNA strand along with a fluorescence quenching protein close by. When the RNA section bonds to RNA from the virus, the sensor’s structure is designed to separate the fluorophore from the quenching protein, which allows the fluorophore to light up in response to a certain wavelength of light. In the case of Fluorescein, it responds to blue light by releasing green light.

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Thread:

Read it. Read the whole thing. This is a common experience when seeing a doctor while non-white, or even (often) as not a cis-man. I have no doubt that if she didn’t have all these people working to help her, she’d be dead at the hands of this doctor’s arrogance (and yes, racism and sexism).

You want to know why POCs (especially Black and Indigenous) are dying in greater numbers? Look no further than this thread.

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FB_IMG_1588724975144

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That’s horrific


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https://www.cvs.com/minuteclinic/covid-19-testing

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that’s not how this works. that’s not how any of this works.

i guess then we shouldn’t count traffic fatalities if the people were driving, because it’s well known if they hadn’t been driving they wouldn’t have died

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Like those apocryphal thousand Inuit words for snow, perhaps Scots has a thousand words for “idiot”

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That is absolutely fucking horrifying and I am ashamed that someone of my profession would treat a human being, any human being, in this fashion. This is a physician who needs to be reported to the medical board for unprofessional conduct. Thank god she had advocates to stand up for her! But of course, most do not. Damn


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And here we go with “It’s the coloreds” again

Throw in “The Mark of The Beast” and we have the makings of a horror movie!

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I have to come back to this. First, because you mentioned belief again. I told you before what my scepticism is based on. It is based in knowledge, not belief. It is not expert knowledge in this particular field of virology or clinical research, but based on my scientific training. I am sceptical of myself as well, but when I look at the available data and something contradicts this data, I question both the old and the new data. In this case, as posted above, the old data wins my trust.

As a statistician, you will know that priors are sometimes referred to as ‘statistical belief’. You could also say a priori assumptions which are based on previous observation. Sorry, but I have to hammer that point, because belief is also used to refer to religions dogma: I don’t trust this research based on my prior knowledge, as imperfect as it may be.

I guess we are on the same page, and this is just semantics (plus some language barrier since English is not my first language), but we have a public discussion here regarding important findings during the worst crisis since WWII. Some people might read our discussion. I hope it helps someone.

I am sceptical about much data right now, but I am also putting my trust - not a belief - in science. And if I sense something fishy about scientific findings, I highlight that. Your post, however, said:

This seems to close to being sceptical of the expert opinion. I do trust some data more than others. It is difficult to choose which data to trust, but I hopefully made clear above why I don’t trust the short communication that they have ID’d a Covid-19 case in France in December. I implicitly mentioned it above, and I assume you are aware of it, but for everyone else I want to emphasise: it is not a full research paper, but a short communication - this means it still should be good science, but is a quicker way of publishing some results which, while usually of high standard, sometimes also puts something in the research community to be torn apart later.

This is possibly such a case.

I apparently was even to moderate in my scepticism above.

  • they should have presented results of confirmation testing on other PCR sequences
  • if they can detect the virus with the rPCR, they should also be able to sequence the full genome, hence addressing which clade the virus is from
  • their test results might even be a false positive because they used a very high concentration of genetic material in their positive control samples, which elevates the probabilities of spillover

Add the lack of sero-conversion testing (antigene tests) and we end up with a paper the person who leads the workgroup which developed the test they used is very sceptical about. He’s rather friendly, still, but firm in his doubtfulness.

Bottom line: if we do not see additional well-checked evidence, it stays unlikely that the virus was already active in France in December, let alone in November.

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Hear that Wisconsin?

FYI


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The Sun has betrayed me!

The astrologer João Bidu who predicted 2020 ‘lighter’ says that ‘nobody expected a coronavirus’.

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Who wants to bet the Trump admin would give him a job offer for doing a stunt like this?

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