Black truffles contain 'bliss molecules' not unlike those found in cannabis


Neat! I had always naively assumed it was the intense umami notes that made them so satisfying (and perhaps that factors into it). But as long as I don’t have to smell them every day when I walk into a room or kitchen steeped with truffle scent I seriously just feel relaxed and smile.

As an aside, if you are in the US the truffle salt from Cost Plus is probably the best value to get that flavor. It is still $12 for a small container, but it is so intense it can last years. I’ve had a million truffle infused whatsits, and that is my favorite.


I’m so sorry.

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There is just so much evidence supporting evolution that it is almost rediculous to believe otherwise. I guess Adam and Eve had to happen for Christ to give his life for their original sin, and evolution invalidates Christianity.

At any rate, I’d love to try some of those truffles, but the price is just barely out of my range…

Michael Backes writes:

[Evidence that] truffles produce endocannabinoids is just the latest evidence that fungi are more closely related to animals than plants.

A pretty ridiculous statement, but Mr. Backes probably thinks cannabis itself is our second cousin.

Here’s a fun paper about aspects of truffle genomes.

Probably explains the anxiety i get from eating them.

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is it? Oh, well, based on what you project he must be thinking… of course he thinks that absurd thing you made up and put on him! The ridicule. Not the statement.

Nobody likes ridicule, and it never adds much, would you agree?


I’m missing something here. Citric acid is a primary component of lemons. Cacao is a primary component of chocolate. Diacetyl is a primary component of popcorn. So what are you getting at?

that the truffle salt (or the smell) that you love may well be manufactured rather than harvested, I believe was his point.

Testy this morning, Acer?

But, my bad. It turns out there’s lots of genetic evidence that fungi are more closely related to humans than to flowering plants. Making my statement even more ridiculous is the realization that this is actually fairly old news.

In my defense, the Italian authors of the linked paper simply suggest that the presence of an endocannabinoid synthesis (ECS) pathway leading to anandamide, which is a human endocannabinoid, “might be an ancient attractant to truffle eaters, that are well-equipped with endocannabinoid-binding receptors.”

As far as I can tell, anandamide is not produced by Cannabis. Instead, it binds to the same receptors that THC uses.

Do not tell the DEA :hushed:


Truffle flavored products don’t contain any truffles.

If there was anything to this story, wouldn’t Beef Borguignon be seasoned with weed instead of thyme?

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I see what you are saying. The brand I buy lists black truffle on the ingredient list. (Literally salt, black truffle). No idea if they are French, Chinese, or Oregon though–likely cheap Chinese fungus.

-edit- and almost certainly has 2,4-dith added. But considering how delicious it is I’m not gonna loose too much sleep :smile:

Here is an example where you can see the ingredients. This one absolutely has manufactured truffle flavor, and 5% by weight of fungus likely means they used bad truffles. But categorically saying truffle flavored anything is wholely manufactured is… Err… Not true?

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It’s weird to see the headline describe the ‘bliss molecules’ the study found -
N-arachidonoylethanolamine, aka anandamide - as “not unlike those found in cannabis.”

In fact, they are rather unlike those found in cannabis - structurally and chemically, they’re quite dissimilar.

But they’re identical to one of the naturally-occurring endocannabinoid neurotransmitters in the human body.

Now, it’s true that, even though the phytocannabinoids in cannabis are structurally rather unlike anandamide, they do affect the same CB1 and CB2 receptors that anandamide does.

In that sense - and pretty much that sense alone - they’re similar

But saying they’re ‘not unlike’ one another is sort of like finding beta-endorphin in a fungus and then proclaiming that the fungus contains “euphoria molecules not unlike heroin” because heroin affects the same human neural receptors that beta-endorphin does.

The most interesting part (to me at least) is that truffles have both the human neurotransmitter anandamide and the underlying enzymes that support the endocannabinoid signaling system in humans - but they do so without themselves having the CB1 and CB2 neural receptors that form that system in humans.

But I guess that’s not nearly as clicky as ‘bliss molecules not unlike cannabis.’


What’s easier than digging them up yourself? Raiding kitchens and beating the hell out of chefs for them!

Combine that with civil forfeiture and the high price of black truffles, and I think we just figured out a way to finance the War on Drugs boys!


Damn, I really could use some “Bliss Molecules” right now.

Don’t worry, this is one of them classy drugs, with culinary applications and historical use among respectable ethnic groups and whatnot. It’s cool.


Don’t tell the Mormons either… You will spoil their savory supper.


It’s a FUNGUS. You people are eating FUNGUS!!!