Yes, I think she’s smart enough to know that she’s done shitty evil deeds for shitty evil people and, in fact, is a shitty evil person herself.
However, I don’t think she thinks she has done anything wrong. She might admit to mistakes but I don’t think she stays up at night worrying about the harm she has inflected on other people. Cory Robin’s book about Clarence Thomas changed my mind about Thomas and I think much of his argument applies to Rice. The shorter is that they both have grafted radical Libertarianism on to a modified Talented 10th/Black separatist perspective. I think they think they are helping “their” race by becoming powerful and anything that smacks of social progress or anti-racism or whatever is bad largely because it depends on the good will of others and lessens their own access to power.
This may be too subtle of a reading of Rice (and Thomas) but I think it allows them to justify ignoring (or participating in!) various racist institutions, even if those very institutions hurt them along the way. Arguably, they are no more or less corrupt than your average Libertarian. High moral ground for Rice and Thomas means finding a place were they are insulated from dealing with the consequences of their actions (and, hey, high places are good for bombing).